As an emerging therapy in the market, BNCT has received attention from more and more medical institutions across the globe with its low cost, high response rate, short treatment time and non-intrusive features.
The research bottleneck remained until Dr. GP Yeh, an American born Chinese expert in high-energy physics, developed the accelerator technology for producing adequate number of neutrons by building on the proton technology in the National Fermi Accelerator Laboratory (FERMILAB) in the United States, which marked a major stride in the development of BNCT.
Based on the German National Innovation Model and ecosystem network investment strategy as the core investment philosophy, we have launched the SP to realize the value investments in the BNCT industry.
To accomplish the abovementioned investment objectives, we comply with the regulations of relevant supervisory authorities by setting up a fund offering and management framework in compliance with Economic Substance Act, international anti-money laundering regulations and fund governance standards for safeguarding the interests of fund investors and building the bridge between market capital and development of BCNT industry to realize the goal of industrialization and strive for a higher return for the investors.
The total size of this fund is 200 million US dollars and the first fundraising to reach an amount of 80 million US dollars is under way.
|Low medication cost||Low equipment cost||No need for hospitalization|
|The cost of treatment is lower than current target drugs and immunotherapy.||More accurate than proton therapy or heavy particle therapy and lower equipment cost.||In contrast with 15-day hospital observation stay for patients receiving general cancer treatments, European and American patients do not need to stay in hospital for observation after BNCT.|
The key points of BNCT market development hypothesis are as follows:
|There have been nearly
|The development of
|Suitable for intro of
Global new cancer cases
Boron neutron capture therapy (BNCT) is a binary cancer treatment. In cancer cells, when an atom absorbs low-energy thermal neutrons, a cytotoxicity event occurs.
This remarkable treatment was proposed by GORDAN L. LOCHER in 1936, shortly after the discovery of neutrons, and since 1950, clinical and chemical research related to BNCT has seen progress.Boron compounds are easily incorporated into organic structures, and their chemical properties have been extensively studied。This is an ideal treatment as it can kill cancer cells while preserving healthy ones.
BNCT, like proton and heavy particle therapy, is a type of radiotherapy and is also a developing cancer treatment method. It works by using boron to absorb neutrons and then split them into lithium and alpha particles to treat cancer. The range of damage to cancer cells is only 5-10μm without affecting surrounding healthy cells.
New anticancer compounds over710
The above information shows that there are still opportunities for the development of new therapies in the huge cancer treatment market. Humans have not yet found a truly effective way to fight cancer, and physics-based radiotherapy is also developing rapidly.
For the steps of modern boron neutron capture treatment
|F18-BPA-PET is usually used to confirm the extent of tumor absorption of BPA before treatment, that is, calculate the ratio of tumor/normal tissue (T/N) BPA concentration.|
|The patient is simulated by computer tomography and the images are transmitted to the software to calculate the dose distribution.。|
|After the prescribed dose and treatment plan are confirmed, the patient is injected with BPA for several hours before receiving neutron irradiation.|
BNCT, a cancer treatment method booming worldwide, can currently be applied to at least 12 cancer treatments. With the continuous investment of relevant medical and research institutions around the world, it is expected that it will gradually be applied to more kinds of cancer treatments. The types of cancers that have been clinically effective are as follows：
|01.Brain tumors||02.Colorectal tumors||03.Malignant meningioma||04.Liver metastasis|
|05.Head and neck tumors||06.Genital tumors||07.Glioblastoma||08.Breast cancer|
|09.Melanoma||10.Radio-resistant tumors||11.Children brain tumors||12.Spinal glioma|